Overview

Polymyxin B (500000 IU) Injection is a potent antibiotic used in hospitals to treat severe Gram-negative bacterial infections, particularly those resistant to other antibiotics.

Key Benefits

• Effective against multidrug-resistant Gram-negative bacteria
• Used in critical care for bloodstream, respiratory, urinary, and intra-abdominal infections
• Often reserved for serious hospital-acquired infections

Composition

Each vial contains: Polymyxin B 500000 IU

How It Works

Polymyxin B targets the bacterial cell membrane, disrupting its integrity and leading to cell death. It is especially effective against Pseudomonas aeruginosa, Acinetobacter baumannii, and Klebsiella pneumoniae.

Usage Directions

• Administered intravenously in a hospital setting under medical supervision
• Dosage and frequency as per infection severity and patient weight
• Hydration and kidney monitoring recommended during treatment

Possible Side Effects

• Nephrotoxicity (kidney damage)
• Neurotoxicity (numbness, dizziness)
• Injection site reactions
• Allergic reactions

Precautions

• Not for use in outpatient settings
• Requires regular renal function monitoring
• Inform your doctor if pregnant, breastfeeding, or having kidney issues

Storage Instructions

• Store in a refrigerator (2°C–8°C)
• Protect from light and moisture
• Keep out of reach of children

Manufacturer

Cipla Ltd.