Phenylephrine Hydrochloride Injection 10 mg/mL (Frenin)

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Phenylephrine Hydrochloride Injection 10 mg/mL (Frenin)

Intensive vasopressor injection used for acute hypotension during anesthesia or septic shock in clinical/critical settings.

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SKU: PHEN-FR-10 Categories: , Tag:

Form: Sterile aqueous injection solution

Manufacturer: Generic Indian Pharmaceutical Manufacturers

Country of Origin: India

Composition

Phenylephrine Hydrochloride 10 mg per mL (injection)

Pack Size

1 mL single-dose vial

Form

Sterile aqueous injection solution

Manufacturer

Generic Indian Pharmaceutical Manufacturers

Country of Origin

India

Usage Category

Hypotension / Anesthesia-Induced Low BP / Septic or Vasodilatory Shock

Dosage Regimen

**IV Bolus (diluted to 100 µg/mL)**: 40–100 µg every 1–2 min, max 200 µg. **IV Infusion (diluted to 20 µg/mL)**: 10–35 µg/min for anesthesia; 0.5–6 µg/kg/min for septic shock, titrate to response.

Onset & Duration

Onset: immediate (IV); Duration: minutes to hours depending on infusion. Half-life ~5 min.

Mechanism of Action

Selective α₁-adrenergic agonist—vasoconstriction increases systemic vascular resistance and blood pressure.

Storage Conditions

Store at 20–25 °C; protect from light. Diluted solutions stable ≤4 h (RT) or ≤24 h refrigerated.

Prescription Status

Rx only

Administration Route

Intravenous – bolus or continuous infusion after proper dilution. Not for direct IV push undiluted.

Shelf Life

24 months (vial)

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