Overview

Efavirenz + Emtricitabine + Tenofovir DF Tablet is a once-daily fixed-dose combination used in first-line therapy for HIV-1 infection. It combines the NNRTI efavirenz with two NRTIs—emtricitabine and tenofovir disoproxil fumarate—to interrupt viral replication at multiple enzyme targets.

Mechanism of Action

Efavirenz (NNRTI) binds to and inactivates HIV reverse transcriptase. Emtricitabine and tenofovir (NRTIs) inhibit viral DNA chain elongation by competing with natural nucleotides.

Dosage & Administration

Take one tablet once daily at bedtime on an empty stomach to minimize central nervous system side effects and improve adherence. Swallow whole; do not chew or crush. ([turn0search3], [turn0search16])

Side Effects & Precautions

• Common: dizziness, insomnia, vivid or abnormal dreams, headache, nausea.
• Serious: lactic acidosis, liver toxicity, renal/bone toxicity (from TDF), psychiatric effects.
• Caution: not suitable in pregnancy (EFV is teratogenic), severe renal/hepatic impairment; monitor labs regularly. ([turn0search0], [turn0search4])

Disclaimer

This content is for product listing purposes only and is not a substitute for medical advice. Use strictly under medical supervision.