Overview

Colistimethate Sodium (1Million IU) Injection is a polymyxin antibiotic used for the treatment of severe infections caused by multidrug-resistant Gram-negative bacteria, particularly in ICU and critical care settings.

Key Benefits

• Effective against carbapenem-resistant organisms
• Used in pneumonia, bloodstream, and urinary tract infections
• Essential for ICU patients with life-threatening infections

Composition

Each vial contains: Colistimethate Sodium 1Million IU

How It Works

Colistimethate disrupts the bacterial cell membrane by interacting with phospholipids, leading to cell death, especially in resistant Gram-negative pathogens.

Usage Directions

• Reconstitute as directed and administer via IV under medical supervision
• Dose varies depending on infection severity and renal function
• Always follow hospital protocol or doctor’s prescription

Possible Side Effects

• Nephrotoxicity (kidney damage)
• Neurotoxicity (dizziness, confusion)
• Injection site reactions

Precautions

• Renal function must be monitored regularly
• Not recommended in patients with myasthenia gravis
• Pregnant women should use only if clearly needed

Storage Instructions

• Keep refrigerated between 2°C and 8°C
• Protect from light and keep out of reach of children

Manufacturer

Cipla