Abamune-L Tablet contains Abacavir 600 mg and Lamivudine 300 mg, two NRTIs used together in HIV-1 combination therapy to inhibit reverse transcriptase and reduce viral replication.

Mechanism of Action

Both Abacavir and Lamivudine act as nucleoside reverse transcriptase inhibitors, blocking the enzyme required for viral DNA synthesis and inhibiting HIV replication. ([turn0search0], [turn0search2])

Dosage & Administration

Take one tablet once daily at the same time each day, with or without food. Do not split or crush the tablet. ([turn0search11])

Side Effects & Precautions

• Common: headache, fatigue, nausea, rash, fever.
• Serious: hypersensitivity reactions—HLA-B*5701 screening is recommended before initiating Abacavir. Use caution in pregnancy and avoid alcohol. Monitor hepatic function regularly.

Disclaimer

For product listing purposes only. This information is not a substitute for medical advice. Always follow healthcare provider instructions.

Tenofovir Disoproxil Fumarate 300 mg Tablet is an oral nucleotide reverse transcriptase inhibitor used in the treatment of HIV-1 and chronic hepatitis B infections, typically taken once daily as part of combination therapy.

Mechanism of Action

Tenofovir disoproxil is converted intracellularly to tenofovir, which inhibits reverse transcriptase and DNA polymerase, preventing viral replication in HIV and HBV. :contentReference[oaicite:0]{index=0}

Dosage & Administration

Recommended dose: one 300 mg tablet once daily, with or without food. :contentReference[oaicite:1]{index=1} Use in adults and children ≥12 years or ≥35 kg.

Side Effects

Common: nausea, diarrhoea, headache, dizziness. Long-term use may affect kidney function and bone mineral density. :contentReference[oaicite:2]{index=2}

Dosage Adjustments & Precautions

Use with caution in renal impairment; dosage interval adjustments may be needed. Monitor renal function. :contentReference[oaicite:3]{index=3}

Disclaimer

Provided for product listing purposes only. Not medical advice; consult a healthcare professional before use.