Overview

Tenofovir Disoproxil Fumarate 300 mg Tablet is an oral nucleotide reverse transcriptase inhibitor used in the treatment of HIV-1 and chronic hepatitis B infections, typically taken once daily as part of combination therapy.

Mechanism of Action

Tenofovir disoproxil is converted intracellularly to tenofovir, which inhibits reverse transcriptase and DNA polymerase, preventing viral replication in HIV and HBV. :contentReference[oaicite:0]{index=0}

Dosage & Administration

Recommended dose: one 300 mg tablet once daily, with or without food. :contentReference[oaicite:1]{index=1} Use in adults and children ≥12 years or ≥35 kg.

Side Effects

Common: nausea, diarrhoea, headache, dizziness. Long-term use may affect kidney function and bone mineral density. :contentReference[oaicite:2]{index=2}

Dosage Adjustments & Precautions

Use with caution in renal impairment; dosage interval adjustments may be needed. Monitor renal function. :contentReference[oaicite:3]{index=3}

Disclaimer

Provided for product listing purposes only. Not medical advice; consult a healthcare professional before use.